Nucleic acid double helix

‘Quadruple Helix’ DNA Strains Seen In Human Cells For The First Time

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Disclose TV January 21 2013 (Thanks, Cliff)

Cambridge University scientists say they have seen four-stranded DNA at work in human cells for the first time.The famous “molecule of life”, which carries our genetic code, is more familiar to us as a double helix.But researchers tell the journal Nature Chemistry that the “quadruple helix” is also present in our cells, and in ways that might possibly relate to cancer.

They suggest that control of the structures could provide novel ways to fight the disease.

“The existence of these structures may be loaded when the cell has a certain genotype or a certain dysfunctional state,” said Prof Shankar Balasubramanian from Cambridge’s department of chemistry.

“We need to prove that; but if that is the case, targeting them with synthetic molecules could be an interesting way of selectively targeting those cells that have this dysfunction,” he told BBC News.

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The Cosmic Serpent: DNA and the Origins of Knowledge

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Deoxy | August 10 2012 | Thanks, Annette

Q&A with Jeremy Narby by Todd Stewart

Could you sum up your book “The Cosmic Serpent, DNA and the Origins of Knowledge”?

Research indicates that shamans access an intelligence, which they say is nature’s, and which gives them information that has stunning correspondences with molecular biology.

Your hypothesis of a hidden intelligence contained within the DNA of all living things is interesting. What is this intelligence?

Intelligence comes from the Latin inter-legere, to choose between. There seems to be a capacity to make choices operating inside each cell in our body, down to the level of individual proteins and enzymes. DNA itself is a kind of “text” that functions through a coding system called “genetic code,” which is strikingly similar to codes used by human beings. Some enzymes edit the RNA transcript of the DNA text and add new letters to it; any error made during this editing can be fatal to the entire organism; so these enzymes are consistently making the right choices; if they don’t, something often goes wrong leading to cancer and other diseases. Cells send one another signals, in the form of proteins and molecules. These signals mean: divide, or don’t divide, move, or don’t move, kill yourself, or stay alive. Any one cell is listening to hundreds of signals at the same time, and has to integrate them and decide what to do. How this intelligence operates is the question.

DNA has essentially maintained its structure for 3.5 billion years. What role does DNA play in our evolution?

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